![]() ![]() Conditions that affect the life of the red blood cell will affect the A1C. Hemoglobin is the major oxygen-carrying protein of the blood. The hemoglobin A1C looks at the amount of sugar on the hemoglobin molecule. A surprising number of my patients prefer shots, even though oral treatment is just as effective. ![]() B-12 can be absorbed orally if given in high-enough doses. Pernicious anemia is diagnosed now by finding the antibodies to intrinsic factor, and is treated by giving B-12 by injection, usually once a month, although a single injection in theory lasts much longer. Without B-12, the body cannot make blood cells effectively, causing the anemia, but severe cases can cause damage to the nerves. Those cells also make a protein called intrinsic factor, which is necessary for efficient vitamin B-12 absorption. It is an autoimmune disease where the body attacks cells that make acid in the stomach. Pernicious anemia is not such a rare condition. Do you feel there could be any relationship between the pernicious anemia condition and my A1C? Because of the rarity of my condition (pernicious anemia), there seems to be very little, if any, research of its impact on various medical issues. ![]() ![]() My daily glucose level reading is very sensitive, almost overly so, to levels of stress in my life. I am also a diabetic for more than 10 years, with my A1C remaining in the 6.1-6.5 range over that time. Roach: I have had pernicious anemia for about eight years and must have an injection of vitamin B-12 every three weeks to stay alive. ![]()
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